ALS — regained movements and improved swallowing

Clinical Case Observation: Amyotrophic Lateral Sclerosis (ALS)

Patient: Ilaria Baldi, 43 years | Italy

Patient Background

Ilaria Baldi, a 43-year-old woman from Italy, was diagnosed with amyotrophic lateral sclerosis (ALS) in 2022. The initial presentation involved progressive weakness of the right hand. Over time, the condition led to increasing limitations in both upper and lower limb mobility, accompanied by difficulties with swallowing and reduced bulbar function.

By the time she presented at BioCells Medical, the patient experienced significant challenges affecting motor control, daily activities, and overall functional independence.

Clinical Approach at BioCells Medical

In July 2025, Ilaria began an individualised autologous regenerative medicine protocol at BioCells Medical. The treatment strategy was developed based on her neurological status, disease progression, and comprehensive medical evaluation.

The protocol included:

• Autologous mesenchymal stem cells (MSCs)

• Autologous T-regulatory cells (Tregs)

• Combined intravenous and intrathecal administration, delivered over two treatment days

All procedures were performed under continuous medical supervision in accordance with established clinical and safety standards.

Post-Treatment Observations

In the weeks following the treatment, the patient’s family reported functional changes that were monitored during follow-up communication with the medical team. These observations included:

• ability to stand and take several supported steps

• clearer speech

• the ability to perform small voluntary movements with the left hand and fingers,

• improved strength and mobility of the right leg,

• return of tongue mobility, which had been absent for several months,

• restored ability to independently reposition in bed, including turning from a supine position to either side.

These changes positively affected daily functioning and comfort.

Follow-Up and Ongoing Monitoring

Ilaria remains under ongoing medical observation following her first treatment cycle. Her neurological status and functional capacity continue to be monitored over time. Additional treatment cycles and supportive measures are being considered based on clinical evolution and patient-specific goals.

Clinical Context

This clinical case illustrates the potential functional changes that may be observed following a personalised regenerative medicine approach in a patient with ALS. At BioCells Medical, each protocol is carefully adapted to the individual patient’s condition, disease stage, and medical profile, with close medical supervision throughout the process.

Because ALS presents differently in each individual, all patients are assessed on a case-by-case basis to determine the most appropriate medical strategy.

Medical Consultation

If you or a loved one is living with ALS and seeking professional medical guidance, you may request a free medical consultation with the BioCells Medical team.

Each case is reviewed individually to determine whether a personalised regenerative medicine approach may be clinically appropriate.