Multiple Sclerosis — improved strength, restored independence in daily activities

Clinical Case Observation: Secondary Progressive Multiple Sclerosis (SPMS)

Patient: Yulia Sergeeva, 35 years | Bishkek, Kyrgyzstan

Patient Background

Yulia Sergeeva, a 35-year-old woman from Bishkek, Kyrgyzstan, was diagnosed with multiple sclerosis at the age of 16. From the age of 22, the disease entered a progressive phase, leading to a gradual decline in motor function. By 2020, she had lost the ability to walk and became wheelchair-dependent, with pronounced motor impairment predominantly affecting the right side of her body.

At the time of presentation at BioCells Medical, the condition was associated with long-standing disability, reduced muscle strength, impaired fine motor control, and limitations in daily independence.

Clinical Approach at BioCells Medical

In 2024, Yulia began a fully personalised regenerative medicine programme at BioCells Medical. The treatment strategy was designed based on disease duration, neurological status, and functional priorities, with the aim of supporting neurological function, motor capacity, and long-term stability.

The therapeutic programme included:

• Bone marrow extraction and cultivation of autologous neuroinduced stem cells, with a preparation period of 2–4 weeks,

• Systemic intravenous infusion of stem cells and concentrated exosomes,

• Combined intrathecal and intranasal administration of cells and exosomes over two consecutive treatment days,

• A personalised rehabilitation programme, developed and supervised by specialised rehabilitation professionals.

All procedures were carried out under structured medical supervision and integrated with ongoing functional training.

Post-Treatment Observations

Following the treatment programme, the patient reported gradual and progressive functional changes, including:

• improved overall well-being and physical resilience,

• increased muscle strength in both upper and lower limbs,

• improved neurological stability, with reduced episodes of overheating,

• enhanced fine motor control.

By the 28th day after treatment, Yulia was able to:

• use her right hand to cut food independently,

• actively propel her wheelchair by turning the wheels without assistance,

• transfer independently in and out of the wheelchair, a function she had not regained for several years.

These improvements developed progressively and were reported as stable over time.

Follow-Up and Ongoing Monitoring

Yulia continues her therapeutic pathway with regular physical training and rehabilitation exercises. Ongoing follow-up indicates sustained functional stability, with her family reporting meaningful improvements in independence, confidence, and overall quality of life.

Clinical monitoring remains focused on maintaining achieved gains and supporting further functional adaptation.

Clinical Context

This clinical case illustrates how a stage-adjusted, personalised regenerative medicine approach, combined with structured rehabilitation, may support functional capacity in patients with long-standing progressive multiple sclerosis. At BioCells Medical, treatment strategies are developed individually and adapted over time, with continuous medical oversight and integration of regenerative and rehabilitative modalities.

Medical Consultation

Patients and families affected by progressive multiple sclerosis who are seeking professional medical guidance may request a free medical consultation with the BioCells Medical team.

Each case is reviewed individually to determine the most appropriate, personalised regenerative care strategy.